This report is anchored to the health knowledge base and cross-checks the new round against the existing historical trends. Numeric markers get Plotly trend charts; qualitative/PCR/stool descriptor results are shown as dated history tables so they are not turned into fake numbers.
Late-2025 data could still be read as “low-grade gut inflammation + iron/platelet consequences.” This round breaks that linkage. Calprotectin is now fully normal, but FOB and stool RBCs turned positive. That means the stool signal is no longer mainly about mucosal inflammation; it is now about possible bleeding/local injury. This is the single most important conceptual update from the round.
Ferritin improved (35.28 → 54.01) and hemoglobin normalized (13.1 → 14.4), which argues against ongoing major iron-collapse. But serum iron dropped sharply and derived transferrin saturation fell from about 35.5% to 19.1%. So the storage compartment looks better while the immediately available iron picture looks weaker. That combination is exactly why the new positive stool-blood result matters.
WBC 13.1 and platelets 494 say the reactive/thrombotic cluster is not gone. The normalized calprotectin means the driver is less likely to be active mucosal gut inflammation alone. Bleeding/iron loss, smoking/inflammatory burden, transient infection/stress, or another reactive source remain plausible. The KB rule still stands: if platelets stay >450 after the reactive drivers settle, clonal workup deserves re-entry.
ApoB 66.31 is good. HbA1c is excellent. Triglycerides are normal. HDL is still favorable and less bizarrely high than before. But LDL 79/ApoB 66 do not erase the structural-risk question created by very high Lp(a). The KB position still applies: keep modifiable apoB burden low and use imaging to find out what the arteries and aortic valve are actually doing.
This round does not support an ongoing march into subclinical hypothyroidism. TSH 1.75 is a clean reversal from 3.61 and makes thyroid a much lower-priority explanation for anything happening right now.
IgA is now high enough to deserve a real look, most likely as a polyclonal/reactive phenomenon but not something to simply hand-wave away. B12 at 231 is not catastrophic, but given the drop from 396 it is low enough to justify a functional check if you want to know whether it is clinically meaningful.
Availability and prices cross-checked live from Biomed’s tariff table today.
| Biomed test | Fee | Why it matters now |
|---|---|---|
| Fibrinogen | $5.00 | Best cheap add-on for the inflammatory-thrombotic cluster behind platelets + WBC + Lp(a). This round is missing it. |
| CBC/Hg | $2.50 | Useful as an early repeat to see whether WBC 13.1 and platelets 494 are transient or persistent. Better done as a short-interval recheck than forgotten. |
| Ferritin | $7.50 | Not because today’s ferritin is bad — it is improved — but because a short-interval repeat is the cleanest way to see whether the positive stool-blood signal is translating into renewed iron-store loss. |
| Biomed test | Fee | Why it matters now |
|---|---|---|
| FOB (Fecal Occult Blood) | $7.50 | Only if you want a confirmatory repeat from a separate sample. Repeating it immediately is lower-yield than acting on the current positive result, but it can help if you suspect sample contamination. |
| Calprotectin /Stool | $65.00 | Not my preferred immediate repeat because it is already clearly normal at 13.3. The current question is bleeding, not whether inflammation is still active. |
| Biomed test | Fee | Why it matters now |
|---|---|---|
| IgG | $10.00 | Checks whether this is a broader quantitative immunoglobulin pattern instead of isolated IgA. |
| IgM | $10.00 | Pairs with IgG/IgA to define the immunoglobulin pattern. |
| Protein Electrophoresis | $25.00 | Best Biomed screening step to separate broad polyclonal elevation from a sharper monoclonal pattern. |
| Urine Analysis Complete | $2.00 | Cheap screen for protein/renal clues if you want to be tidy about the elevated-IgA differential. |
| Immunofixation Electrophoresis | $80.00 | Higher-cost escalation if electrophoresis is abnormal or if you want the more decisive upfront screen. |
| Biomed test | Fee | Why it matters now |
|---|---|---|
| PSA Total | $10.00 | Repeat under standardized conditions: avoid ejaculation and vigorous cycling for 48h first. |
| PSA Free | $15.00 | Best paired add-on if repeating PSA now. A favorable free/total ratio makes benign explanations more likely. |
| Biomed test | Fee | Why it matters now |
|---|---|---|
| Homocysteine total | $25.00 | Biomed has this; it is the practical functional follow-up when MMA is not on the tariff list. Best interpreted with B12, folate history, and kidney function. |
| Biomed test | Fee | Why it matters now |
|---|---|---|
| TPO Ab (Anti Microsomal, Anti TPO) | $15.00 | Only if you still want to settle the prior thyroid question. The urgency dropped a lot because TSH normalized. |
| Free PSA / PSA Free | $15.00 | Listed separately on the tariff; included above, repeated here because this is more useful than panic-repeating total PSA alone. |
Open the rows that matter most. The high-impact markers are expanded by default.
High leukocytosis again. This is not a tiny drift: 13.1 reopens the same elevated-WBC pattern seen in Aug/Nov 2025. Because CRP is only 2.91 and fecal calprotectin is now normal, this looks less like a strong active gut-inflammatory flare and more like a reactive/transient hematologic signal that should be rechecked with CBC rather than ignored.
Relative neutrophil percentage is still within range. The issue is the high total WBC count, so the overall pattern is leukocytosis with a neutrophil-leaning differential rather than an isolated differential abnormality.
In range. Down versus the prior measurement.
Above range/target. Down versus the prior measurement.
Above range/target. Up versus the prior measurement.
Above range/target. Down versus the prior measurement.
Normal and better than the Dec lower reading. This goes with the improved hemoglobin/hematocrit picture.
Clearly improved versus Dec (13.1 → 14.4). That is reassuring: there is no current iron-deficiency anemia pattern here. The catch is that occult blood loss can exist before hemoglobin falls, so the positive stool blood result still matters.
Recovered from the Dec dip and now comfortably normal. This supports the point that you are not currently manifesting overt anemia.
Red-cell indices are currently normal. That argues against established microcytic iron-deficiency anemia right now, although it does not exclude early or intermittent iron loss.
Red-cell indices are currently normal. That argues against established microcytic iron-deficiency anemia right now, although it does not exclude early or intermittent iron loss.
Red-cell indices are currently normal. That argues against established microcytic iron-deficiency anemia right now, although it does not exclude early or intermittent iron loss.
Persistent thrombocytosis remains very real. 494 is above Dec 439 and fits the KB concern that reactive drivers have not fully switched off. The most important update is that calprotectin normalized but occult blood turned positive, so the platelet story now points less toward active mucosal inflammation and more toward unresolved bleeding/iron-loss or another reactive driver. If platelets stay >450 after the bleeding/iron picture settles, JAK2/CALR/MPL workup moves back toward center stage.
Right at the upper limit and slightly better than Dec. This still fits the KB picture of low-grade chronic inflammation rather than acute flare. It is not the main story in this round.
Normal and basically unchanged from late 2025. This is one reason the current round does not look like a major systemic inflammatory spike.
This is one of the best results in the whole packet. 141 → 87.7 → 13.3 is a decisive normalization, which strongly weakens the idea that active gut mucosal inflammation is driving the current picture. It also sharpens the importance of the separate stool blood signal: inflammation improved, but bleeding evidence appeared.
This is the most actionable red flag in the stool results. A positive occult blood result does not tell you the source, but together with microscopic stool RBC presence it means the bleeding question is not closed. The normalized calprotectin makes an inflammatory-colitis explanation less likely and pushes attention toward intermittent bleeding/local lesions (diverticular, hemorrhoidal, fissure, other lower-GI source) rather than active inflammatory mucosal disease.
| Date | Value |
|---|---|
| 2026-04-19 | POSITIVE |
| 2025-12-23 | NEGATIVE |
Microscopic stool RBC presence supports the FOB result rather than leaving it as a lonely false-positive. It still needs clinical context, but it is a real bleeding signal until disproved.
| Date | Value |
|---|---|
| 2026-04-19 | Presence + |
| 2025-12-23 | Absence |
Absence of stool WBC fits the normalized calprotectin and argues against an acute inflammatory/infectious colitis picture.
| Date | Value |
|---|---|
| 2026-04-19 | Absence |
| 2025-12-23 | Absence |
Semi-liquid stool is compatible with ongoing symptom activity, but by KB rules symptom texture is not a bleeding-risk marker. It belongs on the symptom side of the dashboard, not the hemorrhage side.
| Date | Value |
|---|---|
| 2026-04-19 | Semi-liquide |
| 2025-12-23 | Soft |
Yellow stool is nonspecific and does not counter or prove the occult blood result.
| Date | Value |
|---|---|
| 2026-04-19 | Yellow |
| 2025-12-23 | Yellow |
No signal here. This part of the stool microscopy does not point toward parasitic or eosinophilic explanations.
| Date | Value |
|---|---|
| 2026-04-19 | Absence |
| 2025-12-23 | Absence |
No signal here. This part of the stool microscopy does not point toward parasitic or eosinophilic explanations.
| Date | Value |
|---|---|
| 2026-04-19 | Absence |
| 2025-12-23 | Absence |
No signal here. This part of the stool microscopy does not point toward parasitic or eosinophilic explanations.
| Date | Value |
|---|---|
| 2026-04-19 | Negative |
| 2025-12-23 | Negative |
No signal here. This part of the stool microscopy does not point toward parasitic or eosinophilic explanations.
| Date | Value |
|---|---|
| 2026-04-19 | Absence |
| 2025-12-23 | Absence |
No signal here. This part of the stool microscopy does not point toward parasitic or eosinophilic explanations.
| Date | Value |
|---|---|
| 2026-04-19 | Absence |
| 2025-12-23 | Absence |
This is better than the Dec low of 35.3 and argues against progressive collapse of iron stores right now. But it does NOT fully close the iron-loss question, because serum iron has dropped sharply, derived transferrin saturation is much lower, and stool occult blood is now positive. The iron story improved on storage markers but became messier on utilization/loss markers.
Serum iron has fallen hard versus Dec (19.9 → 11.64). Serum iron is noisy, but in this context the drop matters because it lines up with lower derived transferrin saturation and a new positive stool blood signal. On its own this would be weak; together it keeps occult blood loss on the table.
TIBC remains within range and is slightly higher than Dec. With iron lower, the more useful derived conclusion is that transferrin saturation has softened materially rather than that TIBC itself is abnormal.
In range. Up versus the prior measurement.
Normal transferrin does not rescue the iron picture. The important signal is that transport capacity looks intact while available iron delivery looks weaker than in Dec, which is why the derived transferrin saturation matters more than this isolated value.
Total cholesterol is normal and stable. The more decision-relevant markers remain LDL and ApoB.
Still normal, but notably higher than Dec’s ultra-low 0.62. This is not worrisome in isolation; it just means the lipid panel is less “perfect-looking” than the prior round.
Still strong, but importantly lower than the prior 2.53 peak. That actually softens the earlier HDL-U-curve concern in the KB and is easier to interpret as simply favorable rather than unusually high.
Respectable, but not ultra-low. In ordinary screening this would look good. In the KB’s Lp(a)-driven risk framing, 79 mg/dL is acceptable but still above the “drive LDL as low as feasible / often <55 if true very-high-risk disease burden is shown” logic. So this is good control, not maximal control.
ApoB remains good. 66.31 is only slightly above the prior 63.9 and still sits inside the KB’s broad risk goal band (<65–80). This does not erase Lp(a)-driven risk, but it does show that the modifiable apoB-containing particle burden is being kept fairly low.
Excellent and stable. This remains one of the cleanest reassuring anchors in the whole profile: good glycemic control is not the problem here.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Reassuring. The liver profile is clean, which makes alcohol-related current biochemical liver injury an unlikely explanation for the current abnormalities.
Normal. No pancreatic signal here.
Normal kidney function marker. Good baseline if contrast imaging is ever needed.
Normal. No electrolyte disturbance signal in this round.
Normal. No electrolyte disturbance signal in this round.
Normal. No electrolyte disturbance signal in this round.
Normal. No electrolyte disturbance signal in this round.
This is a major change and one of the most reassuring results in the packet. The prior “TSH drift toward subclinical hypothyroidism” concern has eased sharply: 3.61 → 1.75. That makes an active thyroid problem much less urgent right now and weakens the idea that thyroid drift is currently amplifying Lp(a) risk.
Worth respecting, not panicking over. 2.85 is above the lab’s listed range but still below the KB’s age-adjusted 50s threshold of ~3.5. The direction matters more than the raw panic threshold here, so a standardized repeat PSA — ideally with free PSA if you want more signal — is reasonable.
Normal. This weakens the gastrin/hypergastrinemia branch of the bloating differential.
Back down into the low-normal zone. 231 is not frank deficiency, but it reopens the “functional B12 deficiency?” question because serum B12 alone can miss it. Given the drop from 396, homocysteine at Biomed is a reasonable clarifier if you want to know whether this is merely low-normal or biologically meaningful.
Comfortably replete. No issue here; vitamin D status is being maintained.
Useful logistic information: A positive (A Rh+).
| Date | Value |
|---|---|
| 2026-04-19 | TYPE (A) Rhesus (+) |
Unexpectedly high and important. Total IgA at 634.7 is a new abnormality not explained away by this round’s otherwise normal liver panel and normalized calprotectin. The most likely broad frame is a polyclonal/reactive immune signal rather than a monoclonal one, but it deserves characterization rather than assumption: at Biomed the logical next steps are IgG, IgM, protein electrophoresis, and urine analysis.
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
| 2024-08-21 | NEG |
| 2019-09-04 | NEG |
| 2018-02-06 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
| 2020-10-28 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
| 2020-10-28 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
| 2024-08-21 | NEG |
| 2019-09-04 | NEG |
| 2018-02-06 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
| 2024-08-21 | NEG |
| 2019-09-04 | NEG |
| 2018-02-06 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | POS |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | POS |
Negative on this round. This panel does not show evidence of active detection for this organism/pathogen.
| Date | Value |
|---|---|
| 2026-04-22 | NEG |
| 2025-09-12 | NEG |
| 2024-12-09 | NEG |